1. Chemical Bioconjugation of Proteins in an Undergraduate Lab: One-pot Oxidation and Derivatization of the N-Terminus
    Yates, N. D. J., Brabham, R. L., Spears, R. J., Keenan, T., Halliwell, P. A., Pugh, D. P., Parkin, A., Hurst, G. H. & *Fascione, M. A.
    J. Chem. Edu., 2019In press


  1. Ionisation bias undermines the use of MALDI for estimating peptide deamidation: synthetic peptide studies demonstrate ESI gives more reliable response ratios
    Simpson, J. P., Fascione, M. A., Bergstrom, E., Wilson, J. C., Collins, M. J., Penkman, K. E. H. & Thomas-Oates, J. E.
    Rapid Commun. Mass Spect.,  2019, In Press


  1. The characterisation of a galactokinase from Streptomyces coelicolor
    *Keenan, T., Mills, R., Pocock, E., Budhadev, D., Parmeggiani, F., Flitsch, S. L. & Fascione, M. A.
    Carbohydr. Res., 2019, 472, 132-137


  1. Using Automated Glycan Assembly (AGA) for the Practical Synthesis of Heparan Sulfate Oligosaccharide Precursors
    Budhadev, D., Saxby, K., Walton, J., Davies, G. J., Tyler, P., Schworer, R. & *Fascione, M. A.
    Org. Biomol. Chem., 2019, 17, 1817-1821 (highlighted as a 'Hot article' and in the 'New Talent' collection)

AGA HS_graphical abstact


  1. Site-Selective C-C Modification of Proteins at Neutral pH Using Organocatalyst-Mediated Cross Aldol Ligations
    Spears, R. J.; Brabham, R. L.; Budhadev, D.; Keenan, T.; McKenna, S.; Walton, J.; Brannigan, J. A.; Brzozowski, A. M.; Wilkinson, A. J.; Plevin, M. P.; *Fascione, M. A.
    Chem. Sci., 2018, 9, 5585-5593 (highlighted as a 'Hot article')

fig 1 final revised

  1. Pd decaging graph abstractMethodologies for wiring redox proteins/enzymes to electrode surfaces
    Yates, N. D. J.; Fascione, M. A.; Parkin. A.
    Chem. Eur. J., 2018, 24 (47), 12164-12182.

Chem eur J cover

  1. Palladium-unleashed proteins: gentle aldehyde decaging for site-selective protein modification
    Brabham, R. L.; Spears, R. J.; Walton, J.; Tyagi, S.; Lemke, E. A.; *Fascione, M. A.
    Chem. Commun., 2018, 54 (42), 1501-1504.


  1. Molecular recognition-mediated transformation of single-chain polymer nanoparticles into crosslinked polymer films
    Mahon, C. S.; McGurk, C. J.; Watson, S. M. D.; Fascione, M. A.; Sakonsinsiri, C.; Turnbull, W. B.; Fulton, D. A.
    Angew. Chem. Int. Ed., 2017, 56 (42), 12913-12918.


  1. Pyrrolysine amber stop codon suppression: development and applications
    Brabham, R. L.; *Fascione, M. A.
    ChemBioChem. 201718 (20), 1973-1983

Figure 01

  1. Chiral auxiliaries in stereoselective glycosylation reactions
    Brabham, R. L.; *Fascione, M. A.
    in Selective Glycosylations: Synthetic Methods and Catalysts, ed. C. S. Bennet, Wiley-VCH, Weinheim, Germany, 2017, ch. 5, pp. 97-112.
  1. Site-selective incorporation and ligation of protein aldehydes
    Spears, R. J.; *Fascione, M. A.
    Org. Biomol. Chem. 2016, 14, 7622-7638. Highlighted as a "Hot Article".


  1. Compact, polyvalent mannose-quantum dots as sensitive, ratiometric FRET probes for multivalent protein-ligand interactions
    Guo, Y.; Sakonsinsiri, C.; Nehlmeier, I.; Fascione, M. A.; Zhang. H; Pohlman, S.; Turnbull, W. B.; Zhou, D.
    Angew. Chem. Int. Ed. 2016, 55 (15), 4738-4742. Highlighted as a VIP (Very Important Paper), and on back cover.
    publication12back cover
  1. Mechanistic investigations into the application of sulfoxides in carbohydrate synthesis
    *Fascione, M. A.; Brabham, R.; Turnbull, W. B.
    Chem. Eur. J. 2016, 22, 3916-3928.
  1. Templating carbohydrate-functionalised polymer-scaffolded dynamic combinatorial libraries
    Mahon, C. S.; Fascione, M. A.; Sakonsinsiri, C.; McAllister, T. E.; Turnbull, W. B.; Fulton, D. A.;
    Org. Biomol. Chem. 2015, 13, 2756-2761.
  1. A protein-based pentavalent inhibitor of the Cholera Toxin B-subunit
    Branson, T. R.; McAllister, T. E.; Garcia-Hartjes, J.; Fascione, M. A.; Ross, J. F.; Posthuma-Trumpie, G. A.; Wennekes, T.; Zuilhof, H.; Turnbull, W. B.
    Angew. Chem. Int. Ed. 2014, 32, 8323-8327. Highlighted as a VIP (Very Important Paper).
  1. Efficient N-terminal labelling of proteins by use of Sortase
    Williamson, D.; Fascione, M. A.; Webb, M. E.; Turnbull, W. B.
    Angew. Chem. Int. Ed. 2012, 51, 9377-9380.
  1. Mechanistic studies on a sulfoxide transfer reaction mediated by diphenyl sulfoxide/triflic anhydride
    Fascione, M. A.; Adshead, S. J.; Mandal, P. K.; Kilner, C. A.; Leach, A.G.; Turnbull, W. B.
    Chem. Eur. J. 2012, 18, 2987-2997.
  1. Stereoselective glycosylations using oxathiane spiroketal glycosyl donors
    Fascione, M. A.; Webb, N. W.; Kilner, C. A.; Warriner, S. L.; Turnbull, W. B.
    Carbohydr. Res. 2012, 348, 6-13.
  1. Do glycosyl sulfonium ions engage in neighboring group participation? A study of oxathiane glycosyl donors and the basis for their stereoselectivity
    Fascione, M. A.; Kilner, C. A.; Leach, A.G.; Turnbull, W. B.
    Chem. Eur. J. 2012, 18, 321-333.
  1. Benzyne arylation of oxathiane glycosyl donors
    Fascione, M. A.: Turnbull, W. B.
    Beilstein J. Org. Chem. 2010, 6, No. 19.
  1. Stereoselective glycosylations using oxathiane glycosyl donors
    Fascione, M. A.; Adshead, S. J.; Kilner, C. A.; Leach, A.G.; Turnbull, W. B.
    Chem. Commun. 2009, 39, 5841-5843. Highlighted as a Hot Article in ChemComm and Chemistry & Industry.
  1. A natural carbohydrate substrate for Mycobacterium tuberculosis methionine sulfoxide reductase A
    Stalford, S.A.; Fascione, M.A.; Sasindran, S.A.; Chatterjee, D.; Dhandayuthapani, S.; Turnbull, W.B.
    Chem. Commun. 2009, 1, 110-112.
  1. Product Class 14: glycosyl sulfur, selenium and tellurium compounds
    Turnbull, W.B.; Fascione, M.A.; Stalford, S.A.
    Science of Synthesis, 2007, 29, 923-969.